caDNAno is open-source software for design of 3D DNA origami nanostructures. This free open source software is based on Adobe AIR platform . It was written with the goal of providing a fast and intuitive means to create and modify DNA origami designs. This free software makes heavy use of several fantastic open-source libraries and resources , especially Papervision3D for 3D rendering, Michael Baczynski’s AS3 data structures and tutorials, the Tango Desktop Project for ico